Katie Wilkinson. Medically Reviewed by:. Visit the coronavirus resource hub. Send us your vaccination card, Check your Vitamin D Levels for free with the purchase of an at-home thyroid test kit Thank you!
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Is Paloma Right For Me? Schedule a free, no-obligation phone consultation with one of our intake specialists to find out more. Schedule a call. Find out if Paloma is right for you. Schedule a free call with one of our health care advisors. Schedule a Call. All rights reserved. The NIDDK conducts and supports clinical trials in many diseases and conditions, including endocrine diseases.
The trials look to find new ways to prevent, detect, or treat disease and improve quality of life. Clinical trials—and other types of clinical studies —are part of medical research and involve people like you.
Find out if clinical studies are right for you. Griffin P. Rodgers explaining the importance of participating in clinical trials. In addition to searching for federally funded studies, you can expand or narrow your search to include clinical studies from industry, universities, and individuals; however, the National Institutes of Health does not review these studies and cannot ensure they are safe.
Always talk with your health care provider before you participate in a clinical study. The NIDDK translates and disseminates research findings to increase knowledge and understanding about health and disease among patients, health professionals, and the public. The thyroid is a small gland in your neck that makes thyroid hormones. It primarily affects middle-aged women, but it also can occur in men and women of any age and in children. Other factors that may contribute to your risk of developing Hashimoto's disease include having another autoimmune disease, such as rheumatoid arthritis , Type 1 diabetes or lupus; a family history of thyroid or other autoimmune diseases ; and exposure to excessive levels of environmental radiation.
You might not notice signs or symptoms of Hashimoto's disease at first, or you may notice a swelling at the front of your throat. Hashimoto's disease typically progresses slowly over years and causes chronic thyroid damage, leading to a drop in thyroid hormone levels in your blood. Your health care provider may test for Hashimoto's disease if you're feeling increasingly tired or sluggish; have dry skin, constipation and a hoarse voice; or have had previous thyroid problems or a goiter.
Treatment for Hashimoto's disease may include observation and use of medications. If there's no evidence of hormone deficiency and your thyroid is functioning normally, your health care provider may suggest a wait-and-see approach. If you need medication, chances are you'll need it for the rest of your life.
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Cause Cause. Hashimoto's syndrome is an autoimmune disorder thought to result from a combination of genetic and environmental factors. Some of these factors have been identified, but many remain unknown. The antibodies mistakenly "attack" the thyroid, resulting in damage to the gland. It is also more common in people who have other family members with the disease.
However, the genetic factors have only a small effect on a person's overall risk of developing this syndrome. Non-genetic factors that may trigger the syndrome in people at risk may include changes in sex hormones particularly in women , viral infections, high cholesterol, vitamin D deficiency, certain medications, exposure to ionizing radiation, and excess consumption of iodine a substance involved in thyroid hormone production. Also, people with autoimmune diseases seem to have a higher risk of developing Hashimoto's syndrome.
Inheritance Inheritance. The way Hashimoto's syndrome may be passed down in a family inheritance pattern is unclear, because many genetic and environmental factors appear to be involved. However, the syndrome can cluster in families, and having a close relative with Hashimoto's syndrome or another autoimmune disorder likely increases a person's risk of developing the syndrome.
Find a Specialist Find a Specialist. Healthcare Resources To find a medical professional who specializes in genetics, you can ask your doctor for a referral or you can search for one yourself.
You can also learn more about genetic consultations from MedlinePlus Genetics. Research Research. Clinical Research Resources The Centers for Mendelian Genomics program is working to discover the causes of rare genetic disorders.
For more information about applying to the research study, please visit their website. Click on the link to go to ClinicalTrials.
Please note: Studies listed on the ClinicalTrials. We strongly recommend that you talk with a trusted healthcare provider before choosing to participate in any clinical study.
Organizations Organizations. Organizations Supporting this Disease. Organizations Providing General Support.
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